How does The Great Depression relate to the novel 'Of Mice and Men'?

the great depression caused lots of men to lose their jobs and this is what of mice and men talks about-people looking for work.How does The Great Depression relate to the novel 'Of Mice and Men'?
The plot concerns poor men trying to escape their economic hardship which has been caused, or at least worsened, by the depression. On a deeper level though, it's really about friendship, loyalty, trust, and the betrayal of trust. It's an appropriate setting because friendships are most tested during times of limited resources.How does The Great Depression relate to the novel 'Of Mice and Men'?
becouse in mice and men the main characters are going from place to place looking for a job, they don't have a house and the whole story are trying to save and settle somewhere.
cos businessmen shot themselves in the head